A cross-sectional questionnaire-based survey was conducted on randomly selected individuals to assess the knowledge, attitude, and practices of rabies among communities in Meta Robi district Oromia, Central Ethiopia. A semi- structured questionnaire was administered to 100 respondents comprised of 51 from rural, 31 urbans, and 18 from town areas. Interestingly, all (100%) of the study participants had heard about rabies from different sources. About 64% of respondents knew the causative agent of rabies while 11% of the participants responded that they do not know the causative agent, and 25% were found to have misperception about causative agent, which was spiritual, starvation, and thirst. This study revealed the respondents have good action towards bitten humans with 36% of them go hospital/clinics, and 30% follow post exposure vaccination while 32% responded follow traditional medicine and 2% replied wash with soup and water. Ninety three percent of the respondents were not experienced for vaccinating their dog while only 7% vaccinated. However, knowledge deficiency was observed regarding cause and mode of transmission of rabies. The degree of rabies awareness and openness to rabies prevention techniques varies generally. Increasing awareness of the community about the disease should be considered for controlling the disease using social medias and formal training by governmental and non-governmental stake holders