Case Reports and Reviews: Open Access

Chondroid Syringoma: Dermoscopic Features and Diagnostic Challenges – A Case Report

Salma Kozmane, Saâdia Boughaleb, Sofia ElHaitamy and Fatimazahra Mernissi

Article DOI: https://doi.org/10.70620/CRROA/v7i1/157

Abstract

Background: Chondroid syringoma is a rare adnexal tumor that originates from sweat glands. It typically presents as a slow-growing, painless, firm, and well-circumscribed cutaneous nodule, most commonly located in the head and neck region. Dermoscopy, a non-invasive diagnostic tool, can aid in differentiating between possible diagnoses.

Case presentation: In the described case of a 29-year-old man with a 1-cm asymptomatic, firm, pinkish-brown nodule on the upper lip, dermoscopic features included a peripheral erythematous rim, linear whitish streaks, white structureless areas, yellowish crust, and irregular brown blotches. Histopathological examination revealed a biphasic tumor architecture with nests of basaloid epithelial cells and myoepithelial strands embedded in a chondromyxoid stroma, confirming the diagnosis of chondroid syringoma.

Conclusion: This case highlights the supportive role of dermoscopy in suggesting the diagnosis of chondroid syringoma and in excluding major differential diagnoses, particularly nodular basal cell carcinoma, although histopathological examination remains mandatory for definitive diagnosis.

Keywords: Adnexal tumor; Chondroid syringoma; Histology.