Case Reports and Reviews: Open Access

Examination of the Relation Between Periodontal Disease Parameters and Chronic Obstructive Pulmonary Disease: A Case-Control Study in Greek Adults

Nikolaos Andreas Chrysanthakopoulos, Panagiotis Andreas Chrysanthakopoulos, and Aggelos Antonios Oikonomou

Abstract

Aim: The aim of the present research was to investigate the association between Periodontal Disease (PD) indices and Chronic Obstructive Pulmonary Disease (COPD) risk in Greek adults. Methods: A sample of 392 individuals who suffered from COPD and 1,803 healthy individuals were participated in the study. COPD diagnosis was based on the Forced Expiratory Volume/1sec (FEV1)/ Forced Vital Capacity (FVC) ratio. The associations between Probing Pocket Depth (PPD), Clinical Attachment Loss (CAL) and Bleeding on Probing (BOP) as PD indices and risk for the development of COPD was assessed using univariate and multivariate logistic regression analysis models. Results: According to multivariate analysis lower socio-economic status (p= 0.000,OR =5.13, 95% CI= 2.53-8.39), smoking (p=0.000, OR= 15,78 95% CI=8,78- 21,6), moderate / severe CAL (p=0.008, OR= 5.03, 95% CI=3.30-7.65), and the presence of BOP (p=0.012,OR= 4,33, 95% CI= 2,88-6,99) were statistically significantly associated with the risk for COPD. CAL and BOP remained to be significantly associated with the risk for COPD after adjusting for socio-economic status and smoking. Conclusion: CAL and BOP as PD indices were statistically significantly associated with the risk of developing COPD.

Keywords: Periodontitis, Chronic Obstructive Pulmonary Disease, Adults