Case Reports and Reviews: Open Access

Traumatic Ulcerative Granuloma With Stromal Eosinophilia (TUGSE) – A Diagnostic Enigma

Abstract

Traumatic Ulcerative Granuloma with Stromal Eosinophilia ulcer of the oral mucosa is recognized as a benign, reactive, and selflimiting lesion with an uncertain pathophysiology that appears as a solitary, rapidly developing ulcer. These lesions can appear in a variety of ways clinically, but most of these instances a complete history and clinical examination can determine both the etiology and the consequence. It is utmost important to recognize these mucosal lesions which are characterized by the presence of indurated elevated borders and mimics malignant ulcers such as squamous cell carcinoma of the mouth. Although most of times a biopsy of such lesions is not required, in certain cases it may be necessary to conduct histological investigations in order to rule out conditions which clinically resemble traumatic lesions; however, the condition tends to resolve on its own. The present case highlights the clinical aspects, etiopathogenesis and histopathology of this uncommon lesion.

Keywords: Traumatic ulcers, Eosinophilic ulcer, Traumatic ulcerative granuloma with stromal eosinophilia, Reactive benign lesion, non-healing ulcer, TUGSE lesions, Squamous cell carcinoma, Oral ulcer.